Neurohacking: rewiring your brain | Don Vaughn | TEDxUCLA – Howtoshtab – how to, lifehacks, tips and tricks

Inside each one of us is a beautiful symphony. Inside each one of us is a beautiful symphony. Inside each one of us is a beautiful symphony. 100 billion neurons firing in concert, constructing this vivid reality we?re living in, 100 billion neurons firing in concert, constructing this vivid reality we?re living in, 100 billion neurons firing in concert, constructing this vivid reality we?re living in, 100 billion neurons firing in concert, constructing this vivid reality we?re living in, and inside each little piece of that neural activity lives a little bit of what makes you, you. and inside each little piece of that neural activity lives a little bit of what makes you, you. and inside each little piece of that neural activity lives a little bit of what makes you, you. After your experiences today, that activity will have shifted and you will never be the same. After your experiences today, that activity will have shifted and you will never be the same.

After your experiences today, that activity will have shifted and you will never be the same. You are inextricably tied to your brain. You are inextricably tied to your brain. When I first learned these principles, when I was sixteen, When I first learned these principles, when I was sixteen, I fell in love with the brain and I?ve been doing neuroscience research ever since. I fell in love with the brain and I?ve been doing neuroscience research ever since. Now one day, we were doing a new MRI experiment and I was surprised because the experiment went well, but much to all of our shock I had a hole in my brain. Now one day, we were doing a new MRI experiment and I was surprised because the experiment went well, but much to all of our shock I had a hole in my brain. Now one day, we were doing a new MRI experiment and I was surprised because the experiment went well, but much to all of our shock I had a hole in my brain. Now one day, we were doing a new MRI experiment and I was surprised because the experiment went well, but much to all of our shock I had a hole in my brain.

Now one day, we were doing a new MRI experiment and I was surprised because the experiment went well, but much to all of our shock I had a hole in my brain. Now one day, we were doing a new MRI experiment and I was surprised because the experiment went well, but much to all of our shock I had a hole in my brain. It was a pretty big one too; it was like 30% of my cerebellum just wasn’t there It was a pretty big one too; it was like 30% of my cerebellum just wasn’t there Which as you might imagine, I was pretty shocked because Which as you might imagine, I was pretty shocked because I didn’t feel like anything about me or my life and my experience of the world had changed, or was missing. I didn’t feel like anything about me or my life and my experience of the world had changed, or was missing. I didn’t feel like anything about me or my life and my experience of the world had changed, or was missing.

I didn’t feel like anything about me or my life and my experience of the world had changed, or was missing. The cerebellum is one of the most fundamental parts of your brain – it has like 80% of all of your neurons. The cerebellum is one of the most fundamental parts of your brain – it has like 80% of all of your neurons. The cerebellum is one of the most fundamental parts of your brain – it has like 80% of all of your neurons. So I got interested? now there?s this collision between what your brain is supposed to do So I got interested? now there?s this collision between what your brain is supposed to do So I got interested? now there?s this collision between what your brain is supposed to do and then what it?s dealt – and somehow it finds a middle ground. and then what it?s dealt – and somehow it finds a middle ground.

I became really interested in the idea of your brain as a dynamic, flexible system. I became really interested in the idea of your brain as a dynamic, flexible system. I became really interested in the idea of your brain as a dynamic, flexible system. And to that end, I want to tell you the story of Cameron Mott. Just after her third birthday, Cameron started having violent seizures. Just after her third birthday, Cameron started having violent seizures. Just after her third birthday, Cameron started having violent seizures. They started becoming worse and worse, and eventually she was losing her ability to speak. They started becoming worse and worse, and eventually she was losing her ability to speak. They started becoming worse and worse, and eventually she was losing her ability to speak.

Doctors diagnosed her with something called Rasmussen?s encephalitis Doctors diagnosed her with something called Rasmussen?s encephalitis and the only real treatment for this was hemispherectomy – cutting out half of her brain. and the only real treatment for this was hemispherectomy – cutting out half of her brain. and the only real treatment for this was hemispherectomy – cutting out half of her brain. Keep in mind that one half of your brain controls and is responsible for movement and sensation in the other half of your body. Keep in mind that one half of your brain controls and is responsible for movement and sensation in the other half of your body. Keep in mind that one half of your brain controls and is responsible for movement and sensation in the other half of your body. Keep in mind that one half of your brain controls and is responsible for movement and sensation in the other half of your body.

Keep in mind that one half of your brain controls and is responsible for movement and sensation in the other half of your body. So this surgery would immediately leave Cameron hemiplegic. So this surgery would immediately leave Cameron hemiplegic. But just four weeks post-op she walked out of the hospital. But just four weeks post-op she walked out of the hospital. But just four weeks post-op she walked out of the hospital. She is still dealing with a bit of hemiplegia and a bit of peripheral vision loss, She is still dealing with a bit of hemiplegia and a bit of peripheral vision loss, She is still dealing with a bit of hemiplegia and a bit of peripheral vision loss, but otherwise she is able to run around with her peers and she is cognitively quite deft – it?s amazing. but otherwise she is able to run around with her peers and she is cognitively quite deft – it?s amazing. but otherwise she is able to run around with her peers and she is cognitively quite deft – it?s amazing.

but otherwise she is able to run around with her peers and she is cognitively quite deft – it?s amazing. Consider that for a second: if I gave you half of a car, or half of a phone, you wouldn’t be going anywhere in LA Consider that for a second: if I gave you half of a car, or half of a phone, you wouldn’t be going anywhere in LA Consider that for a second: if I gave you half of a car, or half of a phone, you wouldn’t be going anywhere in LA Consider that for a second: if I gave you half of a car, or half of a phone, you wouldn’t be going anywhere in LA and you wouldn’t be on Twitter right now tweeting about how mind-expanding TEDxUCLA is and you wouldn’t be on Twitter right now tweeting about how mind-expanding TEDxUCLA is and you wouldn’t be on Twitter right now tweeting about how mind-expanding TEDxUCLA is Because for most devices 50% equals broken, but somehow in this instance with Cameron, 50% is almost equal to 100%.

Because for most devices 50% equals broken, but somehow in this instance with Cameron, 50% is almost equal to 100%. Because for most devices 50% equals broken, but somehow in this instance with Cameron, 50% is almost equal to 100%. Because for most devices 50% equals broken, but somehow in this instance with Cameron, 50% is almost equal to 100%. Because for most devices 50% equals broken, but somehow in this instance with Cameron, 50% is almost equal to 100%. Because for most devices 50% equals broken, but somehow in this instance with Cameron, 50% is almost equal to 100%. Because for most devices 50% equals broken, but somehow in this instance with Cameron, 50% is almost equal to 100%. How is that possible? Well, the remaining part of Cameron?s brain sensed the massive loss of neural tissue Well, the remaining part of Cameron?s brain sensed the massive loss of neural tissue Well, the remaining part of Cameron?s brain sensed the massive loss of neural tissue and it physically rewired and reorganised itself to take over everything that the other half had previously handled.

and it physically rewired and reorganised itself to take over everything that the other half had previously handled. and it physically rewired and reorganised itself to take over everything that the other half had previously handled. and it physically rewired and reorganised itself to take over everything that the other half had previously handled. and it physically rewired and reorganised itself to take over everything that the other half had previously handled. That is an ability known as neuroplasticity. It?s the ability of the brain to change itself – to rewire. That is an ability known as neuroplasticity. It?s the ability of the brain to change itself – to rewire. That is an ability known as neuroplasticity. It?s the ability of the brain to change itself – to rewire. That is an ability known as neuroplasticity. It?s the ability of the brain to change itself – to rewire.

I think it?s not a very good analogy when people say ?your brain is like a computer?. I think it?s not a very good analogy when people say ?your brain is like a computer?. It?s actually just a really bad one because your brain is not static hardware. It?s actually just a really bad one because your brain is not static hardware. It?s actually just a really bad one because your brain is not static hardware. And although the prevailing view in neuroscience for a long time was that the adult brain is a fixed processing unit, And although the prevailing view in neuroscience for a long time was that the adult brain is a fixed processing unit, And although the prevailing view in neuroscience for a long time was that the adult brain is a fixed processing unit, it seems like everyday we find a new result that says that?s not the case at all. it seems like everyday we find a new result that says that?s not the case at all. it seems like everyday we find a new result that says that?s not the case at all. it seems like everyday we find a new result that says that?s not the case at all.

While there is structure to your brain, it is a dynamic, flexible biology. While there is structure to your brain, it is a dynamic, flexible biology. Let me say that again, you and your brain are static but you?re also dynamic – you can change yourself. Let me say that again, you and your brain are static but you?re also dynamic – you can change yourself. Let me say that again, you and your brain are static but you?re also dynamic – you can change yourself. Let me say that again, you and your brain are static but you?re also dynamic – you can change yourself. So the idea worth spreading is this: So the idea worth spreading is this: What if we were able to treat injuries and impairments in an entirely new way, by hacking in to your brain?s ability to rewire itself? What if we were able to treat injuries and impairments in an entirely new way, by hacking in to your brain?s ability to rewire itself? What if we were able to treat injuries and impairments in an entirely new way, by hacking in to your brain?s ability to rewire itself? What if we were able to treat injuries and impairments in an entirely new way, by hacking in to your brain?s ability to rewire itself? What if we were able to treat injuries and impairments in an entirely new way, by hacking in to your brain?s ability to rewire itself? To show you what I mean lets look at how we?ve treated depression.

To show you what I mean lets look at how we?ve treated depression. Since 1952, scientists and doctors have addressed the question of treatment for depression Since 1952, scientists and doctors have addressed the question of treatment for depression Since 1952, scientists and doctors have addressed the question of treatment for depression as a fixed hardware problem where there is a deficiency of ?happy? neurotransmitters, like serotonin, dopamine, norepinephrine. as a fixed hardware problem where there is a deficiency of ?happy? neurotransmitters, like serotonin, dopamine, norepinephrine. as a fixed hardware problem where there is a deficiency of ?happy? neurotransmitters, like serotonin, dopamine, norepinephrine. as a fixed hardware problem where there is a deficiency of ?happy? neurotransmitters, like serotonin, dopamine, norepinephrine. as a fixed hardware problem where there is a deficiency of ?happy? neurotransmitters, like serotonin, dopamine, norepinephrine. And in this context it makes perfect sense that the way to go about it is to discover and design drugs And in this context it makes perfect sense that the way to go about it is to discover and design drugs And in this context it makes perfect sense that the way to go about it is to discover and design drugs which increase those neurotransmitter levels – enter MAOIs, tricyclics, SSRIs, there are hundreds of them but they all work in pretty much the same way.

which increase those neurotransmitter levels – enter MAOIs, tricyclics, SSRIs, there are hundreds of them but they all work in pretty much the same way. which increase those neurotransmitter levels – enter MAOIs, tricyclics, SSRIs, there are hundreds of them but they all work in pretty much the same way. which increase those neurotransmitter levels – enter MAOIs, tricyclics, SSRIs, there are hundreds of them but they all work in pretty much the same way. which increase those neurotransmitter levels – enter MAOIs, tricyclics, SSRIs, there are hundreds of them but they all work in pretty much the same way. which increase those neurotransmitter levels – enter MAOIs, tricyclics, SSRIs, there are hundreds of them but they all work in pretty much the same way. These are marvels of modern medicine I mean on anti-depressants we see about two-thirds of people see some sort of symptom relief.

I mean on anti-depressants we see about two-thirds of people see some sort of symptom relief. I mean on anti-depressants we see about two-thirds of people see some sort of symptom relief. But that still leaves 1.5 million people in the US alone, who are still struggling to enjoy their lives. But that still leaves 1.5 million people in the US alone, who are still struggling to enjoy their lives. But that still leaves 1.5 million people in the US alone, who are still struggling to enjoy their lives. But that still leaves 1.5 million people in the US alone, who are still struggling to enjoy their lives. But that still leaves 1.5 million people in the US alone, who are still struggling to enjoy their lives. Who are becoming disconnected from their friends and their families – it is an awful, debilitating disease. Who are becoming disconnected from their friends and their families – it is an awful, debilitating disease. Who are becoming disconnected from their friends and their families – it is an awful, debilitating disease.

So what if we were able – what would become possible So what if we were able – what would become possible So what if we were able – what would become possible if we addressed the problem from the perspective of neuroplasticity? if we addressed the problem from the perspective of neuroplasticity? So what we?re doing is essentially finding regions in the brain So what we?re doing is essentially finding regions in the brain that show different activation in depressed patients than in normals. that show different activation in depressed patients than in normals. that show different activation in depressed patients than in normals. For example, if someone with depression shows dorsolateral prefrontal cortex is not as active as it is in other brains For example, if someone with depression shows dorsolateral prefrontal cortex is not as active as it is in other brains For example, if someone with depression shows dorsolateral prefrontal cortex is not as active as it is in other brains For example, if someone with depression shows dorsolateral prefrontal cortex is not as active as it is in other brains we actually use electromagnetic currents from devices placed on the scalp to induce neural rewiring in those areas.

we actually use electromagnetic currents from devices placed on the scalp to induce neural rewiring in those areas. we actually use electromagnetic currents from devices placed on the scalp to induce neural rewiring in those areas. we actually use electromagnetic currents from devices placed on the scalp to induce neural rewiring in those areas. we actually use electromagnetic currents from devices placed on the scalp to induce neural rewiring in those areas. So in the case of the area that was less active than normal, we give a pulse, So in the case of the area that was less active than normal, we give a pulse, we stimulate it, we do whatever we can over several session to say can we up-regulate that, we stimulate it, we do whatever we can over several session to say can we up-regulate that, we stimulate it, we do whatever we can over several session to say can we up-regulate that, can we make this brain essentially pushed back towards normal behaviour – one area at a time. can we make this brain essentially pushed back towards normal behaviour – one area at a time.

can we make this brain essentially pushed back towards normal behaviour – one area at a time. While this is a new technology, some of the pioneering work by Doctor Jonathan Downer at the University of Toronto While this is a new technology, some of the pioneering work by Doctor Jonathan Downer at the University of Toronto While this is a new technology, some of the pioneering work by Doctor Jonathan Downer at the University of Toronto While this is a new technology, some of the pioneering work by Doctor Jonathan Downer at the University of Toronto shows nearly a 33% remission rate for treatment-resistant depression shows nearly a 33% remission rate for treatment-resistant depression which is depression where patients have seen no relief from therapy. which is depression where patients have seen no relief from therapy. which is depression where patients have seen no relief from therapy. They’ve seen no relief from anti-depressants, and they?re running out of options. They’ve seen no relief from anti-depressants, and they?re running out of options. Another wonderful thing about the idea of neuroplasticity is that while drugs are very specific on a molecular level Another wonderful thing about the idea of neuroplasticity is that while drugs are very specific on a molecular level Another wonderful thing about the idea of neuroplasticity is that while drugs are very specific on a molecular level Another wonderful thing about the idea of neuroplasticity is that while drugs are very specific on a molecular level Another wonderful thing about the idea of neuroplasticity is that while drugs are very specific on a molecular level they?re quite general still in their delivery often affecting a whole host of parts around the body that we didn’t intend, they?re quite general still in their delivery often affecting a whole host of parts around the body that we didn’t intend, they?re quite general still in their delivery often affecting a whole host of parts around the body that we didn’t intend, leading to the laundry list of side effects that you?re probably use to hearing at rapid speed at the end of drug commercials.

leading to the laundry list of side effects that you?re probably use to hearing at rapid speed at the end of drug commercials. leading to the laundry list of side effects that you?re probably use to hearing at rapid speed at the end of drug commercials. But neuroplasticity kind of takes the other approach. Instead we?re targeting very large patches of your brain, but we?re leaving the rest alone. Instead we?re targeting very large patches of your brain, but we?re leaving the rest alone. Instead we?re targeting very large patches of your brain, but we?re leaving the rest alone. Instead we?re targeting very large patches of your brain, but we?re leaving the rest alone. We?re now in the midst of the personal medicine revolution – you can sequence your genome ? you can get SNPs – it?s $100/$200. We?re now in the midst of the personal medicine revolution – you can sequence your genome ? you can get SNPs – it?s $100/$200.

We?re now in the midst of the personal medicine revolution – you can sequence your genome ? you can get SNPs – it?s $100/$200. We?re now in the midst of the personal medicine revolution – you can sequence your genome ? you can get SNPs – it?s $100/$200. We?re now in the midst of the personal medicine revolution – you can sequence your genome ? you can get SNPs – it?s $100/$200. I think neuroplasticity can fit into this because the devices that we use can be tailored very specifically to each individual. I think neuroplasticity can fit into this because the devices that we use can be tailored very specifically to each individual. I think neuroplasticity can fit into this because the devices that we use can be tailored very specifically to each individual. I think neuroplasticity can fit into this because the devices that we use can be tailored very specifically to each individual. We can deliver just the right stimulating pulse for John and we can give just the right targeting area for Jenny.

We can deliver just the right stimulating pulse for John and we can give just the right targeting area for Jenny. We can deliver just the right stimulating pulse for John and we can give just the right targeting area for Jenny. We can deliver just the right stimulating pulse for John and we can give just the right targeting area for Jenny. There is a lot of flexibility to make sure we address the fact that we?re as different on the inside There is a lot of flexibility to make sure we address the fact that we?re as different on the inside There is a lot of flexibility to make sure we address the fact that we?re as different on the inside probably more so – than we are on the outside, probably more so – than we are on the outside, and any optimal treatment mechanism should cater to that. and any optimal treatment mechanism should cater to that. To me this seems like science fiction coming true. To me this seems like science fiction coming true.

We are on the frontier of non-invasively being able to rewire your brain to alleviate certain types of mental disorders. We are on the frontier of non-invasively being able to rewire your brain to alleviate certain types of mental disorders. We are on the frontier of non-invasively being able to rewire your brain to alleviate certain types of mental disorders. We are on the frontier of non-invasively being able to rewire your brain to alleviate certain types of mental disorders. While there is certainly debate in the literature as there always is: what?s the right sham? While there is certainly debate in the literature as there always is: what?s the right sham? What?s the right control? Where do you target It doesn’t matter, we?re almost there and the possibilities are startling. It doesn’t matter, we?re almost there and the possibilities are startling. Once we get there, the next question becomes: if we can rewire your brain using devices Once we get there, the next question becomes: if we can rewire your brain using devices Once we get there, the next question becomes: if we can rewire your brain using devices Once we get there, the next question becomes: if we can rewire your brain using devices would it at all be possible to help your brain rewire itself with just your own thoughts? would it at all be possible to help your brain rewire itself with just your own thoughts? would it at all be possible to help your brain rewire itself with just your own thoughts? That seems kind of crazy, but that?s the idea of something called real time neuro-feedback.

That seems kind of crazy, but that?s the idea of something called real time neuro-feedback. That seems kind of crazy, but that?s the idea of something called real time neuro-feedback. Essentially what we?re doing, if you give the example of cocaine addiction, Essentially what we?re doing, if you give the example of cocaine addiction, Essentially what we?re doing, if you give the example of cocaine addiction, we show subjects luring images of cocaine and we induce their craving networks – so these are cocaine addicts. we show subjects luring images of cocaine and we induce their craving networks – so these are cocaine addicts. we show subjects luring images of cocaine and we induce their craving networks – so these are cocaine addicts. we show subjects luring images of cocaine and we induce their craving networks – so these are cocaine addicts.

And then we present them with the real-time feedback of what their brain is actually doing. And then we present them with the real-time feedback of what their brain is actually doing. What is the craving network in your brain really doing? The idea is we?re asking people to surf their mental landscape and do whatever it is they need to do to make that bar go down, The idea is we?re asking people to surf their mental landscape and do whatever it is they need to do to make that bar go down, The idea is we?re asking people to surf their mental landscape and do whatever it is they need to do to make that bar go down, The idea is we?re asking people to surf their mental landscape and do whatever it is they need to do to make that bar go down, which essentially is exploiting whatever conscious control and probably in most cases unconscious control which essentially is exploiting whatever conscious control and probably in most cases unconscious control which essentially is exploiting whatever conscious control and probably in most cases unconscious control which essentially is exploiting whatever conscious control and probably in most cases unconscious control that you have over your own brain to rewire it intelligently at just the right times, with just a little bit of biofeedback.

that you have over your own brain to rewire it intelligently at just the right times, with just a little bit of biofeedback. that you have over your own brain to rewire it intelligently at just the right times, with just a little bit of biofeedback. that you have over your own brain to rewire it intelligently at just the right times, with just a little bit of biofeedback. that you have over your own brain to rewire it intelligently at just the right times, with just a little bit of biofeedback. I think this has real implications for the legal system, I think this has real implications for the legal system, I think this has real implications for the legal system, because we?re getting to the point where our neural chemistry is getting really good. because we?re getting to the point where our neural chemistry is getting really good. We?re now able to give different types of drugs to change mood states, and in one case we as a government are now disarming criminals with drugs. We?re now able to give different types of drugs to change mood states, and in one case we as a government are now disarming criminals with drugs.

We?re now able to give different types of drugs to change mood states, and in one case we as a government are now disarming criminals with drugs. We?re now able to give different types of drugs to change mood states, and in one case we as a government are now disarming criminals with drugs. We?re now able to give different types of drugs to change mood states, and in one case we as a government are now disarming criminals with drugs. We?re now able to give different types of drugs to change mood states, and in one case we as a government are now disarming criminals with drugs. That might sound like a 1984-esque type of statement but consider that we already do it. That might sound like a 1984-esque type of statement but consider that we already do it. That might sound like a 1984-esque type of statement but consider that we already do it.

In California and many other states, we mandate what?s called chemical castration for reoffending sex offenders. In California and many other states, we mandate what?s called chemical castration for reoffending sex offenders. In California and many other states, we mandate what?s called chemical castration for reoffending sex offenders. So they?re forced to take Medroxyprogesterone acetate to reduce their libido – and it?s effective. So they?re forced to take Medroxyprogesterone acetate to reduce their libido – and it?s effective. So they?re forced to take Medroxyprogesterone acetate to reduce their libido – and it?s effective. I?m not here to comment on the morality of the subject, but I do feel that as we look for new ways to rehabilitate criminals, instead of warehouse them, I?m not here to comment on the morality of the subject, but I do feel that as we look for new ways to rehabilitate criminals, instead of warehouse them, I?m not here to comment on the morality of the subject, but I do feel that as we look for new ways to rehabilitate criminals, instead of warehouse them, I?m not here to comment on the morality of the subject, but I do feel that as we look for new ways to rehabilitate criminals, instead of warehouse them, I?m not here to comment on the morality of the subject, but I do feel that as we look for new ways to rehabilitate criminals, instead of warehouse them, neuroplasticity would be an incredible option where before we say ? ?you have to take this drug or we?re not letting you out neuroplasticity would be an incredible option where before we say ? ?you have to take this drug or we?re not letting you out we instead see: is there any possibility for this person to be rewired or to rewire themselves.

we instead see: is there any possibility for this person to be rewired or to rewire themselves. we instead see: is there any possibility for this person to be rewired or to rewire themselves. we instead see: is there any possibility for this person to be rewired or to rewire themselves. And moving beyond deficits, what if instead of just treating deficits we actually use this to improve ourselves And moving beyond deficits, what if instead of just treating deficits we actually use this to improve ourselves And moving beyond deficits, what if instead of just treating deficits we actually use this to improve ourselves And moving beyond deficits, what if instead of just treating deficits we actually use this to improve ourselves just our own impulse control – where we use our own intelligent brain plasticity to modulate and up-regulate just our own impulse control – where we use our own intelligent brain plasticity to modulate and up-regulate just our own impulse control – where we use our own intelligent brain plasticity to modulate and up-regulate just our own impulse control – where we use our own intelligent brain plasticity to modulate and up-regulate just our own impulse control – where we use our own intelligent brain plasticity to modulate and up-regulate just our own impulse control – where we use our own intelligent brain plasticity to modulate and up-regulate just our own impulse control – where we use our own intelligent brain plasticity to modulate and up-regulate our long term decision making, our attention, our impulse control.

our long term decision making, our attention, our impulse control. What if we went to the biofeedback mental gym as much as we went to the real gym What if we went to the biofeedback mental gym as much as we went to the real gym What if we went to the biofeedback mental gym as much as we went to the real gym What if we went to the biofeedback mental gym as much as we went to the real gym and we lifted our behavioural problems with as much vigour as we lift our 45 pound plates? and we lifted our behavioural problems with as much vigour as we lift our 45 pound plates? I think it?s a beautiful idea. I think it?s a beautiful idea. There?s one more application of neuroplasticity I would like to talk to you about, There?s one more application of neuroplasticity I would like to talk to you about, There?s one more application of neuroplasticity I would like to talk to you about, but in order to do so we?re going to run a quick experiment. Everyone look under your seats, some of you will see a pair of earplugs and some of you stole them before the break Everyone look under your seats, some of you will see a pair of earplugs and some of you stole them before the break Everyone look under your seats, some of you will see a pair of earplugs and some of you stole them before the break Everyone look under your seats, some of you will see a pair of earplugs and some of you stole them before the break Everyone look under your seats, some of you will see a pair of earplugs and some of you stole them before the break – I know who you are.

Pull them out! – I know who you are. Pull them out! So here?s the experiment, those of you who have earplugs, you?re going to be Speakers So here?s the experiment, those of you who have earplugs, you?re going to be Speakers So here?s the experiment, those of you who have earplugs, you?re going to be Speakers and everyone else you?re going to be Listeners. Now I?d like you all to meet my friend Mimi. Now I?d like you all to meet my friend Mimi. Mimi is seven months old and she loves to talk. Mimi is seven months old and she loves to talk. When I press play, your job, Speakers, is to mimic what she’s saying, Listeners your job is to see how well they do When I press play, your job, Speakers, is to mimic what she’s saying, Listeners your job is to see how well they do When I press play, your job, Speakers, is to mimic what she’s saying, Listeners your job is to see how well they do When I press play, your job, Speakers, is to mimic what she’s saying, Listeners your job is to see how well they do When I press play, your job, Speakers, is to mimic what she’s saying, Listeners your job is to see how well they do When I press play, your job, Speakers, is to mimic what she’s saying, Listeners your job is to see how well they do Okay, put in your earplugs, and for those of you at home go ahead and plug your ears the old fashion way and see if you can play along.

Okay, put in your earplugs, and for those of you at home go ahead and plug your ears the old fashion way and see if you can play along. Okay, put in your earplugs, and for those of you at home go ahead and plug your ears the old fashion way and see if you can play along. Okay, put in your earplugs, and for those of you at home go ahead and plug your ears the old fashion way and see if you can play along. Okay, put in your earplugs, and for those of you at home go ahead and plug your ears the old fashion way and see if you can play along. Okay, Listeners how did they do? Yeah, like pretty terribly actually, and look, I kind of set you all up to fail on that one, because lip reading is really difficult problem. Yeah, like pretty terribly actually, and look, I kind of set you all up to fail on that one, because lip reading is really difficult problem. Yeah, like pretty terribly actually, and look, I kind of set you all up to fail on that one, because lip reading is really difficult problem.

Yeah, like pretty terribly actually, and look, I kind of set you all up to fail on that one, because lip reading is really difficult problem. Yeah, like pretty terribly actually, and look, I kind of set you all up to fail on that one, because lip reading is really difficult problem. Yeah, like pretty terribly actually, and look, I kind of set you all up to fail on that one, because lip reading is really difficult problem. But lip reading babies who, as all you missed, can make vocalisations without their mouth moving at all But lip reading babies who, as all you missed, can make vocalisations without their mouth moving at all But lip reading babies who, as all you missed, can make vocalisations without their mouth moving at all But lip reading babies who, as all you missed, can make vocalisations without their mouth moving at all and then who speak with toys in their mouth is a really, really difficult problem.

and then who speak with toys in their mouth is a really, really difficult problem. and then who speak with toys in their mouth is a really, really difficult problem. It?s harder than neuroscience. So imagine though that Mimi is your child and this is everyday of your life So imagine though that Mimi is your child and this is everyday of your life So imagine though that Mimi is your child and this is everyday of your life So imagine though that Mimi is your child and this is everyday of your life That?s the reality for deaf parents and over 90% of their children who are hearing-able. That?s the reality for deaf parents and over 90% of their children who are hearing-able. That?s the reality for deaf parents and over 90% of their children who are hearing-able. That?s the reality for deaf parents and over 90% of their children who are hearing-able. This can lead to a real divide between families because parents are unable to engage in traditional baby talk This can lead to a real divide between families because parents are unable to engage in traditional baby talk This can lead to a real divide between families because parents are unable to engage in traditional baby talk This can lead to a real divide between families because parents are unable to engage in traditional baby talk It?s now very clear that traditional baby talk is not the cute or annoying musings of parents It?s now very clear that traditional baby talk is not the cute or annoying musings of parents It?s now very clear that traditional baby talk is not the cute or annoying musings of parents It?s now very clear that traditional baby talk is not the cute or annoying musings of parents but instead it is a tool specifically designed by nature to teach language and to foster connection.

but instead it is a tool specifically designed by nature to teach language and to foster connection. but instead it is a tool specifically designed by nature to teach language and to foster connection. but instead it is a tool specifically designed by nature to teach language and to foster connection. You can imagine if that was gone, it could be a really difficult issue. You can imagine if that was gone, it could be a really difficult issue. You can imagine if that was gone, it could be a really difficult issue. So the question that Doctor Arianna Anderson and myself at UCLA asked was: So the question that Doctor Arianna Anderson and myself at UCLA asked was: So the question that Doctor Arianna Anderson and myself at UCLA asked was: if you can?t get infant vocalisations in through the ears, is there another option? if you can?t get infant vocalisations in through the ears, is there another option? if you can?t get infant vocalisations in through the ears, is there another option? Well, when you scan brains across the population, Well, when you scan brains across the population, Well, when you scan brains across the population, you see that there are very specify parts of your cortex that are devoted to processing one type of sensory modality or another.

you see that there are very specify parts of your cortex that are devoted to processing one type of sensory modality or another. you see that there are very specify parts of your cortex that are devoted to processing one type of sensory modality or another. For example, this morning on the TEDx tour through UCLA?s Staglin Center, For example, this morning on the TEDx tour through UCLA?s Staglin Center, For example, this morning on the TEDx tour through UCLA?s Staglin Center, we see that there?s a very particular part of Stephanie?s brain that lights up to only visual information we see that there?s a very particular part of Stephanie?s brain that lights up to only visual information and independently there?s a completely separate part of the brain that responds only to touch. and independently there?s a completely separate part of the brain that responds only to touch. and independently there?s a completely separate part of the brain that responds only to touch. But here?s where it gets really interesting, when you scan the brains while blind people are feeling braille, But here?s where it gets really interesting, when you scan the brains while blind people are feeling braille, But here?s where it gets really interesting, when you scan the brains while blind people are feeling braille, But here?s where it gets really interesting, when you scan the brains while blind people are feeling braille, But here?s where it gets really interesting, when you scan the brains while blind people are feeling braille, you don’t just get the touch parts of the brain active, you see visual areas active as well.

you don’t just get the touch parts of the brain active, you see visual areas active as well. you don’t just get the touch parts of the brain active, you see visual areas active as well. Similarly when you scan the brains of the deaf population while they?re communicating using sign language Similarly when you scan the brains of the deaf population while they?re communicating using sign language Similarly when you scan the brains of the deaf population while they?re communicating using sign language Similarly when you scan the brains of the deaf population while they?re communicating using sign language you don’t just see the visual areas active from seeing the gestures, but you actually see auditory cortex activated.

you don’t just see the visual areas active from seeing the gestures, but you actually see auditory cortex activated. you don’t just see the visual areas active from seeing the gestures, but you actually see auditory cortex activated. you don’t just see the visual areas active from seeing the gestures, but you actually see auditory cortex activated. Somehow, your brain isn’t just plastic. It?s not just random. Somehow, your brain isn’t just plastic. It?s not just random. It is intelligently plastic and somehow it?s rewiring itself in order to maximise and process as much information from the outside world as possible. It is intelligently plastic and somehow it?s rewiring itself in order to maximise and process as much information from the outside world as possible. It is intelligently plastic and somehow it?s rewiring itself in order to maximise and process as much information from the outside world as possible. It is intelligently plastic and somehow it?s rewiring itself in order to maximise and process as much information from the outside world as possible.

It is intelligently plastic and somehow it?s rewiring itself in order to maximise and process as much information from the outside world as possible. It is intelligently plastic and somehow it?s rewiring itself in order to maximise and process as much information from the outside world as possible. Somehow your brain is learning to see braille and to hear sign language. Somehow your brain is learning to see braille and to hear sign language. Somehow your brain is learning to see braille and to hear sign language. So this is called sensory substitution and the ideas as Paul Bach-y-Rita and David Eagleman So this is called sensory substitution and the ideas as Paul Bach-y-Rita and David Eagleman So this is called sensory substitution and the ideas as Paul Bach-y-Rita and David Eagleman So this is called sensory substitution and the ideas as Paul Bach-y-Rita and David Eagleman So this is called sensory substitution and the ideas as Paul Bach-y-Rita and David Eagleman have exploited is that you can take information from one sense that?s lost, translate it to a different sensor modality and put it in that way have exploited is that you can take information from one sense that?s lost, translate it to a different sensor modality and put it in that way have exploited is that you can take information from one sense that?s lost, translate it to a different sensor modality and put it in that way have exploited is that you can take information from one sense that?s lost, translate it to a different sensor modality and put it in that way have exploited is that you can take information from one sense that?s lost, translate it to a different sensor modality and put it in that way Surprisingly your brain figures it out, because your brain is plastic Surprisingly your brain figures it out, because your brain is plastic This is the idea that we?ve taken and we?ve moved forward with developing an application with a small grant from UCLA called Chatter Baby This is the idea that we?ve taken and we?ve moved forward with developing an application with a small grant from UCLA called Chatter Baby This is the idea that we?ve taken and we?ve moved forward with developing an application with a small grant from UCLA called Chatter Baby This is the idea that we?ve taken and we?ve moved forward with developing an application with a small grant from UCLA called Chatter Baby What Chatter Baby does is it turns auditory information into visual information – it?s a type of sensory substitution.

What Chatter Baby does is it turns auditory information into visual information – it?s a type of sensory substitution. What Chatter Baby does is it turns auditory information into visual information – it?s a type of sensory substitution. What Chatter Baby does is it turns auditory information into visual information – it?s a type of sensory substitution. So now Mimi?s chatter comes alive in visual form – you don’t miss anything now. So now Mimi?s chatter comes alive in visual form – you don’t miss anything now. So now Mimi?s chatter comes alive in visual form – you don’t miss anything now. So now Mimi?s chatter comes alive in visual form – you don’t miss anything now. Even though her lips aren’t moving you can see what?s going on. Even though her lips aren’t moving you can see what?s going on. The idea is that deaf parents can use this tool to learn baby talk and to connect as deeply as possible with their child.

The idea is that deaf parents can use this tool to learn baby talk and to connect as deeply as possible with their child. The idea is that deaf parents can use this tool to learn baby talk and to connect as deeply as possible with their child. The idea is that deaf parents can use this tool to learn baby talk and to connect as deeply as possible with their child. The idea is that deaf parents can use this tool to learn baby talk and to connect as deeply as possible with their child. The idea is that deaf parents can use this tool to learn baby talk and to connect as deeply as possible with their child. We believe that eventually once they become fluent in using this tool, they will be able to hear their child through sight. We believe that eventually once they become fluent in using this tool, they will be able to hear their child through sight.

We believe that eventually once they become fluent in using this tool, they will be able to hear their child through sight. We believe that eventually once they become fluent in using this tool, they will be able to hear their child through sight. and to me that is such an important application of neuroplasticity and to me that is such an important application of neuroplasticity and to me that is such an important application of neuroplasticity and to me that is such an important application of neuroplasticity and to me that is such an important application of neuroplasticity This shows that it?s not just in fun tool for turning auditory information into visuals, This shows that it?s not just in fun tool for turning auditory information into visuals, This shows that it?s not just in fun tool for turning auditory information into visuals, This shows that it?s not just in fun tool for turning auditory information into visuals, but instead sensory processing plasticity, it has the ability to connect deaf parents and their babies but instead sensory processing plasticity, it has the ability to connect deaf parents and their babies but instead sensory processing plasticity, it has the ability to connect deaf parents and their babies that?s the power of plasticity.

But that?s only half the battle. that?s the power of plasticity. But that?s only half the battle. The other part of this disconnect is that when deaf parents aren’t in the same room as their children, The other part of this disconnect is that when deaf parents aren’t in the same room as their children, The other part of this disconnect is that when deaf parents aren’t in the same room as their children, The other part of this disconnect is that when deaf parents aren’t in the same room as their children, they don?t know what mood they?re in and the best baby monitors out there on the market, they don?t know what mood they?re in and the best baby monitors out there on the market, they say yes, there?s sound; no, there?s no sound.

But that doesn’t really tell me what I care about. It doesn’t tell me: is my child happy and content? But that doesn’t really tell me what I care about. It doesn’t tell me: is my child happy and content? But that doesn’t really tell me what I care about. It doesn’t tell me: is my child happy and content? But that doesn’t really tell me what I care about. It doesn’t tell me: is my child happy and content? Or instead are they hungry? Are they crying? Is there something going on that I need to be there and I need to address? Instead, I?m constantly wondering, sound? No sound? I don?t know. Instead, I?m constantly wondering, sound? No sound? I don?t know. Instead, I?m constantly wondering, sound? No sound? I don?t know. So what we?re doing with Chatter Baby is we are gathering the world?s largest database of infant sounds So what we?re doing with Chatter Baby is we are gathering the world?s largest database of infant sounds So what we?re doing with Chatter Baby is we are gathering the world?s largest database of infant sounds So what we?re doing with Chatter Baby is we are gathering the world?s largest database of infant sounds and we?re then using sophisticated mathematics to take that sound and predict what children?s mood states are.

So he?s really hungry and we?re then using sophisticated mathematics to take that sound and predict what children?s mood states are. So he?s really hungry and we?re then using sophisticated mathematics to take that sound and predict what children?s mood states are. So he?s really hungry and we?re then using sophisticated mathematics to take that sound and predict what children?s mood states are. So he?s really hungry The idea is that we can use neuroplasticity to make a real difference in how deaf parents communicate with their children. The idea is that we can use neuroplasticity to make a real difference in how deaf parents communicate with their children. The idea is that we can use neuroplasticity to make a real difference in how deaf parents communicate with their children. The idea is that we can use neuroplasticity to make a real difference in how deaf parents communicate with their children.

I talked to you about now how to treat depression, addiction and sensory impairments using neuroplasticity, I talked to you about now how to treat depression, addiction and sensory impairments using neuroplasticity, I talked to you about now how to treat depression, addiction and sensory impairments using neuroplasticity, I talked to you about now how to treat depression, addiction and sensory impairments using neuroplasticity, I talked to you about now how to treat depression, addiction and sensory impairments using neuroplasticity, I talked to you about now how to treat depression, addiction and sensory impairments using neuroplasticity, but that?s really only the beginning. but that?s really only the beginning. We?re starting to move into diseases you wouldn’t expect would be treated by something like this, like Alzheimer?s and Parkinson?s and stroke.

We?re starting to move into diseases you wouldn’t expect would be treated by something like this, like Alzheimer?s and Parkinson?s and stroke. We?re starting to move into diseases you wouldn’t expect would be treated by something like this, like Alzheimer?s and Parkinson?s and stroke. That?s really just the beginning of what I?ve been calling Neurohacking That?s really just the beginning of what I?ve been calling Neurohacking I don’t mean Neurohacking in the sense that these aren?t thoroughly researched I don’t mean Neurohacking in the sense that these aren?t thoroughly researched they?re really well though out ideas and there?s a lot of literature to support why they work they?re really well though out ideas and there?s a lot of literature to support why they work But in the sense that we?re not directly trying to fix the nuts and the bolts of all these problems But in the sense that we?re not directly trying to fix the nuts and the bolts of all these problems But in the sense that we?re not directly trying to fix the nuts and the bolts of all these problems we?re not trying to change every biochemical cascade that?s going on in the brain – which is essentially the root of the problem we?re not trying to change every biochemical cascade that?s going on in the brain – which is essentially the root of the problem we?re not trying to change every biochemical cascade that?s going on in the brain – which is essentially the root of the problem we?re not trying to change every biochemical cascade that?s going on in the brain – which is essentially the root of the problem But there are a hundred trillion connections in your brain, and each one of them is like a city with a thousand chemical cascades going on But there are a hundred trillion connections in your brain, and each one of them is like a city with a thousand chemical cascades going on But there are a hundred trillion connections in your brain, and each one of them is like a city with a thousand chemical cascades going on But there are a hundred trillion connections in your brain, and each one of them is like a city with a thousand chemical cascades going on It is such a difficult problem, so instead, what I think some of the biggest advances in neuroscience and all of what we?re doing It is such a difficult problem, so instead, what I think some of the biggest advances in neuroscience and all of what we?re doing It is such a difficult problem, so instead, what I think some of the biggest advances in neuroscience and all of what we?re doing It is such a difficult problem, so instead, what I think some of the biggest advances in neuroscience and all of what we?re doing is going to be exploiting this incredible quality of your brain that is uniquely yours, is going to be exploiting this incredible quality of your brain that is uniquely yours, is going to be exploiting this incredible quality of your brain that is uniquely yours, to rewire and reallocate itself based on what it needs.

to rewire and reallocate itself based on what it needs. If we step back for a moment from neuroscience, the question for you I have today is If we step back for a moment from neuroscience, the question for you I have today is If we step back for a moment from neuroscience, the question for you I have today is where in your life are you waiting to understand every little nut and bolt of a problem, every nuance, before you decide to solve it and make a change where in your life are you waiting to understand every little nut and bolt of a problem, every nuance, before you decide to solve it and make a change where in your life are you waiting to understand every little nut and bolt of a problem, every nuance, before you decide to solve it and make a change where in your life are you waiting to understand every little nut and bolt of a problem, every nuance, before you decide to solve it and make a change If you?re trying effect social change in Los Angeles with six million people, If you?re trying effect social change in Los Angeles with six million people, If you?re trying effect social change in Los Angeles with six million people, If you?re trying effect social change in Los Angeles with six million people, there?s probably a couple million don?t want to hear your story and they?re not going to helpful to you.

there?s probably a couple million don?t want to hear your story and they?re not going to helpful to you. But instead of focusing on what?s broken and what doesn’t work, But instead of focusing on what?s broken and what doesn’t work, maybe take a lesson from Neurohacking and use what does still work to get the results you want maybe take a lesson from Neurohacking and use what does still work to get the results you want maybe take a lesson from Neurohacking and use what does still work to get the results you want maybe take a lesson from Neurohacking and use what does still work to get the results you want Thank you! .

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